Article
Multifunctional nature of P fimbriae of uropathogenic Escherichia coli: mutations in fsoE and fsoF influence fimbrial binding to renal tubuli and immobilized fibronectin.
Molecular microbiology - 1 Dec 1991
Westerlund B, van Die I, Kramer C, Kuusela P, Holthöfer H, Tarkkanen A M, Virkola R, Riegman N, Bergmans H, Hoekstra W
Abstract excerpt
P fimbriae of the F7(1) serotype of Escherichia coli are composed of a major subunit, FsoA, and of three minor proteins named FsoG, FsoE, and FsoF. FsoG is the Gal alpha(1-4)Gal-specific lectin. We assessed mutated recombinant strains each deficient in one fimbrial component for adhesion to frozen sections of rat cortical kidney and to fibronectin immobilized on glass. Rat kidney lacks the Gal...
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