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Article

Strategies for dissecting genetic-environmental interactions in neurodegenerative disorders.

Neurotoxicology - 1 Sept 2006

Schmechel Donald E, Browndyke Jeffrey, Ghio Andrew

Abstract excerpt

Complex genetic and environmental interactions contribute to abnormal aging and neurodegenerative disorders. We present information from a series of 1136 consecutive patients presenting with cognitive disorders and show possible significant contribution of toxic environmental and occupational exposures to pathological aging (21% of patients) and interactions of these exposures with common polymorphisms that...

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Identifiers

PMID: 16870258
DOI: 10.1016/j.neuro.2006.05.021

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APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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