Article
The -56T HLA-G promoter polymorphism is not associated with pre-eclampsia/eclampsia in Australian and New Zealand women.
Hypertension in pregnancy - 1 Jan 2006
Doherty Vicki L, Rush Ashley N, Brennecke Shaun P, Moses Eric K
Abstract excerpt
OBJECTIVE: Decreased HLA-G expression has been linked to a number of pregnancy disorders, including preeclampsia, and a genetic basis for HLA-G regulation has yet to be found. The aim of this study was to determine whether a C-to-T base substitution 56 base pairs (bp) upstream from the HLA-G transcription start site is associated with preeclampsia. METHODS: 277 nulliparous women consisting of 113 normotensive,...
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