Article
Non-steroidal anti-inflammatory drug-related hepatic damage in France and Spain: analysis from national spontaneous reporting systems.
Fundamental & clinical pharmacology - 1 Aug 2006
Lapeyre-Mestre Maryse, de Castro Ana Maria Rueda, Bareille Marie-Pierre, Del Pozo Javier Garcia, Requejo Ana Alvarez, Arias Louis Martin, Montastruc Jean-Louis, Carvajal Alfonso
Abstract excerpt
Several non-steroidal anti-inflammatory drugs (NSAIDs) have been associated with liver damage. The aim of this study was to compare proportions of hepatic adverse drug reaction reports associated with NSAIDs in France and Spain. Information from the Spanish and French pharmacovigilance databases were used from 1982 to 2001. To assess the risk of liver injury, the case/non-case methodology was applied, 'cases'...
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