Article
[Genetic features during chronic obstructive pulmonary disease].
Medicina (Kaunas, Lithuania) - 1 Jan 2006
Babusyte Agne, Sitkauskiene Brigita, Sakalauskas Raimundas
Abstract excerpt
Chronic obstructive pulmonary disease is one of the leading causes of mortality, which is caused by the interaction of genetic susceptibility with environmental factors (especially smoking); however, genetic features of chronic obstructive pulmonary disease still remain unknown. The only proven genetic risk factor is severe deficiency of plasma protease inhibitor, alpha-1 antitrypsin. A large number of candidate...
Topics
- Genetic Linkage
- Genetic Markers
- Genetic Predisposition to Disease
- Humans
- Phenotype
- Polymorphism, Genetic
- Pulmonary Disease, Chronic Obstructive
- Respiratory Function Tests
- Risk Factors
- Smoking
- Spirometry
- Xenobiotics
- alpha 1-Antitrypsin
