A genetic study of neurofibromatosis 1 in south-western Ontario. I. Population, familial segregation of phenotype, and molecular linkage.

doi:10.1136/jmg.28.11.746

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Article

A genetic study of neurofibromatosis 1 in south-western Ontario. I. Population, familial segregation of phenotype, and molecular linkage.

Journal of medical genetics - 1 Nov 1991

Rodenhiser D I, Coulter-Mackie M B, Jung J H, Singh S M

Abstract excerpt

This report is concerned with neurofibromatosis type 1 (NF-1, 17q11.2) in south-western Ontario, an ethnically diverse population derived from multiple immigrations. The population incidence, prevalence, and mutation rates for this disease are similar in most racial groups of this population and...

Topics

DNA Probes
Female
Genetic Linkage
Genetics, Population
Heterozygote
Humans
Male
Neurofibromatosis 1
Nucleic Acid Hybridization
Ontario
Phenotype
Polymorphism, Restriction Fragment Length

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