Article
Spot pattern of leopard Danio is caused by mutation in the zebrafish connexin41.8 gene.
EMBO reports - 1 Sept 2006
Watanabe Masakatsu, Iwashita Motoko, Ishii Masaru, Kurachi Yoshihisa, Kawakami Atsushi, Kondo Shigeru, Okada Norihiro
Abstract excerpt
Leopard, a well-known zebrafish mutant that has a spotted skin pattern instead of stripes, is a model for the study of pigment patterning. To understand the mechanisms underlying stripe formation, as well as the spot variation observed in leopard, we sought to identify the gene responsible for this phenotype. Using positional cloning, we identified the leopard gene as an orthologue of the mammalian connexin 40...
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