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Article

Evolutionary rate variation among vertebrate beta globin genes: implications for dating gene family duplication events.

Gene - 15 Sept 2006

Aguileta Gabriela, Bielawski Joseph P, Yang Ziheng

Abstract excerpt

A comprehensive dataset of 62 beta globin gene sequences from various vertebrates was compiled to test the molecular clock and to estimate dates of gene duplications. We found that evolution of the beta globin family of genes is not clock-like, a result that is at odds with the common use of this family as an example of a constant rate of evolution over time. Divergence dates were estimated either with or without...

Topics

Animals
Bayes Theorem
Birds
Databases, Genetic
Evolution, Molecular
Gene Conversion
Gene Duplication
Genetic Variation
Globins
Humans
Likelihood Functions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Marsupialia

Multigene Family

Phylogeny

Time Factors

Vertebrates

Source

Identifiers

PMID: 16843621
DOI: 10.1016/j.gene.2006.04.019

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