Intratumoural heterogeneity of nuclear DNA-content and proliferation in clear cell type carcinomas of the kidney.

doi:10.1007/BF02890405

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Article

Intratumoural heterogeneity of nuclear DNA-content and proliferation in clear cell type carcinomas of the kidney.

Virchows Archiv. B, Cell pathology including molecular pathology - 1 Jan 1991

Baretton G, Kuhlmann B, Krech R, Löhrs U

Abstract excerpt

Clear celled renal carcinomas (n = 37) were investigated by flow cytometry for intratumoural heterogeneity in DNA-ploidy and proliferation (S-phase rate). Using gross sections of the tumours, 178 regions of interest were selected and excised from the paraffin blocks. Of the tumours examined 30% (...

Topics

Adenocarcinoma
Cell Cycle
Cell Division
DNA, Neoplasm
Eosinophilia
Flow Cytometry
Genetic Variation
Humans
Kidney Neoplasms
Ploidies

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