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Article

Intratumoral heterogeneity of DNA content in renal cell carcinoma and its prognostic significance.

Cancer - 15 Aug 1999

Ruiz-Cerdá J L, Hernández M, Sempere A, O'Connor J E, Kimler B F, Jiménez-Cruz F

Abstract excerpt

BACKGROUND: A multiple sampling study was performed on 124 specimens of renal cell carcinomas to analyze the consistency and reliability of DNA measurements. The authors investigated intratumoral DNA heterogeneity and its role as a adverse prognostic factor for disease progression. METHODS: DNA content was analyzed by flow cytometry on three different samples of the same tumor. The Cronbach alpha coefficient was...

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Identifiers

PMID: 10440695
DOI: 10.1002/(sici)1097-0142(19990815)86:4<664::aid-cncr16>3.0.co;2-e

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Source receipt: pubmed, retrieved 7 Sept 2026.

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