Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nuclear DNA analysis: DNA heterogeneity in the monitoring of patients with locally advanced prostatic carcinoma.

European urology - 1 Jan 1992

al-Abadi H, Nagel R

Abstract excerpt

Single-cell DNA cytophotometry was employed to analyze the tumors of 271 patients with locally advanced prostatic carcinoma as to DNA ploidy and heterogeneity and the distribution of the phases of the cell cycle before and during therapy, with the intention of establishing prognostic factors apart from those already known (stage, grade). Follow-up periods ranged from 1 to 9 years. 198 (73%) of the 271 patients...

Topics

Adult
Aged
Aged, 80 and over
Cytophotometry
DNA, Neoplasm
Humans
Male
Middle Aged
Neoplasm Staging
Phenotype
Ploidies
Prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prostatic Neoplasms

Remission Induction

Source

Identifiers

PMID: 1490508
DOI: 10.1159/000474777

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1490508-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nuclear DNA analysis: DNA heterogeneity in the monitoring of patients with locally advanced prostatic carcinoma.PMID 1490508Read ↗

Ploidy level determinations in high-grade and low-grade malignant variants of prostatic carcinoma.Semantic proximity Read ↗

Genotypic characterization of prostatic carcinomas: a combined cytogenetic, flow cytometry, and in situ DNA hybridization study.Semantic proximity Read ↗

DNA Replication Licensing Factors and Aneuploidy Are Linked to Tumor Cell Cycle State and Clinical Outcome in Penile CarcinomaSemantic proximity Read ↗

Ploidy disturbances as an early indicator of intrinsic malignancy in endometrial carcinoma.Semantic proximity Read ↗

Altered mode of allelic replication accompanied by aneuploidy in peripheral blood lymphocytes of prostate cancer patients.Semantic proximity Read ↗

Intratumoural heterogeneity of nuclear DNA-content and proliferation in clear cell type carcinomas of the kidney.Semantic proximity Read ↗

Cytometry and DNA ploidy: clinical uses and molecular perspective in gastric and lung cancer.Semantic proximity Read ↗

Colorectal carcinoma. DNA ploidy pattern and prognosis with reference to tumor DNA heterogeneity.Semantic proximity Read ↗

Tumour heterogeneity of DNA cell cycle variables in breast cancer measured by flow cytometry.Semantic proximity Read ↗

DNA Ploidy and Cell Cycle Analysis in Breast CancerSemantic proximity Read ↗

Stage D1 prostate cancer treated by radical prostatectomy and adjuvant hormonal treatment. Evidence for favorable survival in patients with DNA diploid tumorsSemantic proximity Read ↗

Atypical adenomatous hyperplasia (adenosis) of the prostate: DNA ploidy analysis and immunophenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.