Article
Host invasion during rice-blast disease requires carnitine-dependent transport of peroxisomal acetyl-CoA.
Molecular microbiology - 1 Jul 2006
Ramos-Pamplona Marilou, Naqvi Naweed I
Abstract excerpt
In lower eukaryotes, beta-oxidation of fatty acids is restricted primarily to the peroxisomes and the resultant acetyl-CoA molecules (and the chain-shortened fatty acids) are transported via the cytosol into the mitochondria for further breakdown and usage. Using a loss-of-function mutation in the Magnaporthe grisea PEROXIN6 orthologue, we define an essential role for peroxisomal acetyl-CoA during the host...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.