Article
Specific hydrogen-bonding networks responsible for selective O2 sensing of the oxygen sensor protein HemAT from Bacillus subtilis.
Biochemistry - 11 Jul 2006
Yoshimura Hideaki, Yoshioka Shiro, Kobayashi Katsuaki, Ohta Takehiro, Uchida Takeshi, Kubo Minoru, Kitagawa Teizo, Aono Shigetoshi
Abstract excerpt
HemAT from Bacillus subtilis (HemAT-Bs) is a heme-based O2 sensor protein that acts as a signal transducer responsible for aerotaxis. HemAT-Bs discriminates its physiological effector, O2, from other gas molecules to generate the aerotactic signal, but the detailed mechanism of the selective O2 sensing is not obvious. In this study, we measured electronic absorption, electron paramagnetic resonance (EPR), and...
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