Article
Effect of Factor V Leiden and prothrombin G20210-->A mutations on thromboembolic risk in the national surgical adjuvant breast and bowel project breast cancer prevention trial.
Journal of the National Cancer Institute - 5 Jul 2006
Abramson Neil, Costantino Joseph P, Garber Judy E, Berliner Nancy, Wickerham D Lawrence, Wolmark Norman
Abstract excerpt
BACKGROUND: In the National Surgical Adjuvant Breast and Bowel Project's Breast Cancer Prevention Project (BCPT), tamoxifen use was associated with an increased relative risk for venous thromboembolic events, including deep vein thrombosis and pulmonary emboli, compared with placebo. However, the involvement of hypercoagulability factors in this association is unclear. METHODS: To examine possible associations...
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