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Article

Homozygous MTHFR C677T gene mutation and recurrent stroke in an infant.

Pediatric neurology - 1 Jul 2006

Garoufi Anastasia J, Prassouli Alexia A, Attilakos Achilleas V, Voudris Konstantinos A, Katsarou Eustathia S

Abstract excerpt

The role of homozygosity for the C677T mutation in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene as an independent risk factor for primary and recurrent stroke has been questioned, although recent data appear to be supportive. However, the association of homozygous C677T MTHFR mutation with silent brain infarctions in infancy has not been reported. The authors describe an 11-month-old male who had...

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Identifiers

PMID: 16814086
DOI: 10.1016/j.pediatrneurol.2005.12.007

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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