Article
Genetically modified cyanobacterium Nostoc muscorum overproducing proline in response to salinity and osmotic stresses.
Journal of biosciences - 1 Jun 2006
Bhargava Santosh
Abstract excerpt
In the parent Nostoc muscorum an active proline oxidase enzyme is required to assimilate exogenous proline as a fixed nitrogen source. Cyanobacterial mutants, resistant to growth inhibitory action of proline analogue L-azetidine-2-carboxylate (Ac-R), were deficient in proline oxidase activity, and were over-accumulators of proline. Proline over-accumulation, resulting either from mutational acquisition of the...
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