Article
Genomic variability in field populations of Schistosoma mansoni in Brazil as detected with a ribosomal gene probe.
The American journal of tropical medicine and hygiene - 1 Jan 1991
Vieira L Q, Correa-Oliveira R, Katz N, de Souza C P, Carvalho O S, Araujo N, Sher A, Brindley P J
Abstract excerpt
A cloned fragment of the ribosomal gene of Schistosoma mansoni, pSM 389, which contains part of the small rRNA gene plus a portion of the nontranscribed intergenic spacer, was used in Southern hybridization analyses to investigate genomic variation in natural populations of S. mansoni in Brazil. Genomic DNAs were isolated from schistosomes from infected patients (some of whom did not respond to antischistosomal...
Topics
- Animals
- Blotting, Southern
- Brazil
- DNA
- Genetic Variation
- Humans
- Polymorphism, Restriction Fragment Length
- RNA Probes
- RNA, Ribosomal
- Schistosoma mansoni
- Schistosomiasis mansoni