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Article

Common hepatic nuclear factor-4alpha variants are associated with high serum lipid levels and the metabolic syndrome.

Diabetes - 1 Jul 2006

Weissglas-Volkov Daphna, Huertas-Vazquez Adriana, Suviolahti Elina, Lee Jenny, Plaisier Christopher, Canizales-Quinteros Samuel, Tusie-Luna Teresa, Aguilar-Salinas Carlos, Taskinen Marja-Riitta, Pajukanta Päivi

Abstract excerpt

Hepatic nuclear factor-4alpha (HNF-4alpha), a transcription factor involved in the regulation of serum lipid and glucose levels, has recently been associated with type 2 diabetes. The HNF-4alpha gene (HNF4A) resides on chromosome 20q12-q13.1, which, in addition to type 2 diabetes, has also previously been linked to high triglycerides in Finnish familial combined hyperlipidemia (FCHL) families. FCHL, characterized...

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PMID: 16804065
DOI: 10.2337/db06-0035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Common hepatic nuclear factor-4alpha variants are associated with high serum lipid levels and the metabolic syndrome.PMID 16804065Read ↗

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