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Article

Structural and functional differences between mouse mot-1 and mot-2 proteins that differ in two amino acids.

Annals of the New York Academy of Sciences - 1 May 2006

Deocaris Custer C, Yamasaki Kazuhiko, Kaul Sunil C, Wadhwa Renu

Abstract excerpt

Chaperone functions mediated by the heat-shock protein (HSP) family constitute a fundamental mechanism that governs the life span of organisms. Here we investigated the chaperone activities of the mitochondrial HSP70 protein, mortalin, which is a heat-uninducible stress protein involved in immortalization and tumorigenesis. There are two mortalin alleles, mot-1 and mot-2, in mouse, encoding two distinct proteins....

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Identifiers

PMID: 16803989
DOI: 10.1196/annals.1354.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Structural and functional differences between mouse mot-1 and mot-2 proteins that differ in two amino acids.PMID 16803989Read ↗

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