Article
Neisseria meningitidis NhhA is a multifunctional trimeric autotransporter adhesin.
Molecular microbiology - 1 Aug 2006
Scarselli Maria, Serruto Davide, Montanari Paolo, Capecchi Barbara, Adu-Bobie Jeannette, Veggi Daniele, Rappuoli Rino, Pizza Mariagrazia, Aricò Beatrice
Abstract excerpt
NhhA, Neisseriahia/hsf homologue, or GNA0992, is an oligomeric outer membrane protein of Neisseria meningitidis, recently included in the family of trimeric autotransporter adhesins. In this study we present the structural and functional characterization of this protein. By expressing in Escherichia coli the full-length gene, deletion mutants and chimeric proteins of NhhA, we demonstrated that the last 72...
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