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Inhibitory and Stimulatory Bystander Effects are Differentially Induced by Iodine-125 and Iodine-123

1 Jun 2006

Abstract excerpt

The bystander effect, originating from cells irradiated in vitro, describes responses of surrounding cells not targeted by the radiation. Previously we demonstrated that the subcutaneous injection into nude mice of human adenocarcinoma LS174T cells lethally irradiated by Auger electrons from the decay of DNA-incorporated (125)I inhibits growth of co-injected LS174T cells (inhibitory bystander effect; Proc. Natl....

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PMID: 16802869
DOI: 10.1667/rr3567.1

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