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Article

Does ASPA gene mutation in Canavan disease alter oligodendrocyte development? A tissue culture study of ASPA KO mice brain.

Advances in experimental medicine and biology - 1 Jan 2006

Kumar Shalini, Sowmyalakshmi Rasika, Daniels Sarah L, Chang Ruth, Surendran Sankar, Matalon Reuben, de Vellis Jean

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16802712
DOI: 10.1007/0-387-30172-0_12

Genes

ASPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

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Research trail→

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Does ASPA gene mutation in Canavan disease alter oligodendrocyte development? A tissue culture study of ASPA KO mice brain.PMID 16802712Read ↗

Aspartoacylase-lacZ knockin mice: an engineered model of Canavan disease.Semantic proximity Read ↗

Canavan disease: studies on the knockout mouse.Semantic proximity Read ↗

Uncoupling N-acetylaspartate from brain pathology: implications for Canavan disease gene therapy.Semantic proximity Read ↗

Molecular basis of Canavan's disease: from human to mouse.Semantic proximity Read ↗

Canavan disease: A white matter disorderSemantic proximity Read ↗

Canavan Disease: Genomic Organization and Localization of Human ASPA to 17p13-ter and Conservation of the ASPA Gene during EvolutionSemantic proximity Read ↗

Knock-out mouse for Canavan disease: a model for gene transfer to the central nervous system.Semantic proximity Read ↗

Therapeutic Options in Prevention and Treatment of Aspartoacylase Gene Mutation Resulting Abnormalities in Canavan Disease.Semantic proximity Read ↗

Aberrant neurodevelopment in human iPS cell-derived models of Alexander disease.Semantic proximity Read ↗

Loss of NARS1 impairs progenitor proliferation in cortical brain organoids and leads to microcephaly.Semantic proximity Read ↗

Aspartoacylase supports oxidative energy metabolism during myelination.Semantic proximity Read ↗

Redirecting N-acetylaspartate metabolism in the central nervous system normalizes myelination and rescues Canavan diseaseSemantic proximity Read ↗

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