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Article

The androgen receptor CAG repeat modifies the impact of testosterone on insulin resistance in women with polycystic ovary syndrome.

European journal of endocrinology - 1 Jul 2006

Möhlig Matthias, Jürgens Annette, Spranger Joachim, Hoffmann Kurt, Weickert Martin O, Schlösser Hans W, Schill Thilo, Brabant Georg, Schüring Andreas, Pfeiffer Andreas F H, Gromoll Jörg, Schöfl Christof

Abstract excerpt

OBJECTIVE: Hyperandrogenism is a central feature of the polycystic ovary syndrome (PCOS) and might worsen insulin resistance (IR) often seen in PCOS. Androgens act through the androgen receptor (AR). A polymorphic CAG repeat sequence within the AR gene was reported to modulate its transactivation activity. Therefore, we investigated a putative interaction between testosterone and the CAG repeat length...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16793958
DOI: 10.1530/eje.1.02195

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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