Article
Genetic polymorphisms of phase II metabolic enzymes and lung cancer susceptibility in a population of Central South China.
Disease markers - 1 Jan 2006
Chen Han-chun, Cao Yan-fei, Hu Wei-xin, Liu Xin-fa, Liu Qing-xia, Zhang Ji, Liu Jia
Abstract excerpt
A case-control study was conducted for analyzing the genetic polymorphisms of phase II metabolic enzymes in 97 patients with lung cancer and 197 healthy subjects from Han ethnic group of Hunan Province located in Central South China. The results showed that the frequencies of glutathione S-transferase (GST) M1-null (GSTM1-) or GSTT1-null (GSTT1-) genotype alone, or combined form of both in lung cancer patients...
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