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Article

The Quest for the Mechanism of Melanin Transfer

18 May 2006

Abstract excerpt

Skin pigmentation is accomplished by production of melanin in specialized membrane-bound organelles termed melanosomes and by transfer of these organelles from melanocytes to surrounding keratinocytes. The mechanism by which these cells transfer melanin is yet unknown. A central role has been established for the protease-activated receptor-2 of the keratinocyte which effectuates melanin transfer via phagocytosis....

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PMID: 16787393
DOI: 10.1111/j.1600-0854.2006.00425.x

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