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Article

Reversal of convention: from man to experimental animal in elucidating the function of the renal amiloride-sensitive sodium channel.

Experimental nephrology - 1 Jan 2000

Hummler E

Abstract excerpt

The kidney plays a dominant role in maintaining sodium homeostasis. Despite wide variation in environmental exposure, the osmolality of the extracellular fluid that is determined by the sodium ion concentration is maintained within narrow margins. Derangement in function of proteins that transport Na+ and of those regulating the activity of these sodium-transporting proteins are likely to be responsible for a...

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Identifiers

PMID: 9690087
DOI: 10.1159/000020531

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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