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Article

Enhancement of GLI1-transcriptional activity by β-catenin in human cancer cells

1 Jul 2006

Abstract excerpt

The Hedgehog (Hh) signaling pathway and the Wnt signaling pathway are known to play important roles in carcinogenesis and the progression of various human malignant tumors. Although a relationship between these two pathways has recently been reported, the mechanism by which beta-catenin, one of the key molecules of the Wnt signaling pathway, influences the Hh pathway has not yet been revealed in detail. To...

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PMID: 16786128
DOI: 10.3892/or.16.1.91

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