In situ detection of Epstein-Barr virus and phenotype determination of EBV-infected cells.

doi:10.1385/1-59745-007-3:115

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Article

In situ detection of Epstein-Barr virus and phenotype determination of EBV-infected cells.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2006

Niedobitek Gerald, Herbst Hermann

Abstract excerpt

Epstein-Barr virus (EBV) establishes a lifelong infection of B cells. Consequently, EBV-carrying B cells are present in the peripheral blood as well as in lymphoid and nonlymphoid tissues of most individuals. As a result, the detection by polymerase chain reaction of EBV genomes in DNA extracts from tumor tissues does not permit conclusions as to the precise cellular source of the virus. For a meaningful analysis...

Topics

B-Lymphocytes
Epstein-Barr Virus Infections
Herpesvirus 4, Human
Humans
In Situ Hybridization
Phenotype
RNA, Viral

Source

Open in PubMed

Identifiers

PMID: 16780197
DOI: 10.1385/1-59745-007-3:115

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