Deletion of pseudorabies virus US2 gene enhances viral titers in a porcine cerebral cortex primary culture system.

doi:10.1007/s11262-018-1552-5

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Article

Deletion of pseudorabies virus US2 gene enhances viral titers in a porcine cerebral cortex primary culture system.

Virus genes - 1 Jun 2018

Lyu Chuang, Wang Shuwen, Sun Mingxia, Tang Yandong, Peng Jinmei, Tian Zhijun, Cai Xuehui

Abstract excerpt

Pseudorabies virus (PRV) is a neurotropic virus with the ability to infect peripheral sensory ganglia. The transport of PRV from the peripheral to the central nervous system can cause lethal encephalitis in young piglets. However, the pathogenicity of PRV in the cerebral cortex remains poorly understood. In the present study, we developed a porcine cerebral cortex primary culture system (PCCS) using cerebral...

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PMID: 29541931
DOI: 10.1007/s11262-018-1552-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.