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Article

Poxvirus CD8<sup>+</sup>T-Cell Determinants and Cross-Reactivity in BALB/c Mice

15 Jun 2006

Abstract excerpt

Mouse models of orthopoxvirus disease provide great promise for probing basic questions regarding host responses to this group of pathogens, which includes the causative agents of monkeypox and smallpox. However, some essential tools for their study that are taken for granted with other mouse models are not available for these viruses. Here we map and characterize the initial CD8+ T-cell determinants for...

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Identifiers

PMID: 16775319
DOI: 10.1128/jvi.00427-06

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