Article
Relationship of eye muscle antibodies with HLA phenotypes and thyroid-stimulating immunoglobulins in endocrine orbitopathy.
Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie - 1 Jan 1991
Kahaly G, Moncayo R, Stover C, Beyer J
Abstract excerpt
The relationship between endocrine orbitopathy and Graves' hyperthyroidism is still not clarified. The purpose of this study was to elucidate the incidence of eye muscle antibodies and the relationship with HLA phenotypes and thyroid antibodies in 65 patients with endocrine orbitopathy classes 1-5. Both bovine and abdominal muscles were used as antigens in ELISA systems in which IgG and IgM antibodies were...
Topics
- Adolescent
- Adult
- Aged
- Autoantibodies
- Autoimmune Diseases
- Exophthalmos
- Female
- Graves Disease
- HLA Antigens
- Humans
- Immunoglobulin G