Article
In vivo heteromer formation. Expression of soluble betaA4-crystallin requires coexpression of a heteromeric partner.
The FEBS journal - 1 Jul 2006
Marín-Vinader Laura, Onnekink Carla, van Genesen Siebe T, Slingsby Christine, Lubsen Nicolette H
Abstract excerpt
The beta-crystallins are a family of long-lived, abundant structural proteins that are coexpressed in the vertebrate lens. As beta-crystallins form heteromers, a process that involves transient exposure of hydrophobic interfaces, we have examined whether in vivobeta-crystallin assembly is enhanced by protein chaperones, either small heat shock proteins, Hsp27 or alphaB-crystallin, or Hsp70. We show here that...
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