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Article

Relative efficiencies of the maximum-parsimony and distance-matrix methods of phylogeny construction for restriction data.

Molecular biology and evolution - 1 May 1991

Lin J, Nei M

Abstract excerpt

The relative efficiencies of the maximum-parsimony (MP), UPGMA, and neighbor-joining (NJ) methods in obtaining the correct tree (topology) for restriction-site and restriction-fragment data were studied by computer simulation. In this simulation, six DNA sequences of 16,000 nucleotides were assumed to evolve following a given model tree. The recognition sequences of 20 different six-base restriction enzymes were...

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PMID: 1677154
DOI: 10.1093/oxfordjournals.molbev.a040648

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