Article
The apolipoprotein A-IV Gln360His polymorphism predicts progression of coronary artery calcification in patients with type 1 diabetes.
Diabetologia - 1 Aug 2006
Kretowski A, Hokanson J E, McFann K, Kinney G L, Snell-Bergeon J K, Maahs D M, Wadwa R P, Eckel R H, Ogden L G, Garg S K, Li J, Cheng S, Erlich H A, Rewers M
Abstract excerpt
AIMS/HYPOTHESIS: Individuals with type 1 diabetes have an increased incidence of coronary artery disease (CAD) and a higher risk of cardiovascular death compared with individuals of the same age in the general population. While chronic hyperglycaemia and insulin resistance partially explain excess CAD, little is known about the potential genetic determinants of accelerated coronary atherosclerosis in type 1...
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