Article
Very early prenatal diagnosis of genetic diseases based on coelomic fluid analysis: a feasibility study.
Human reproduction (Oxford, England) - 1 Aug 2006
Jouannic Jean-Marie, Costa Jean-Marc, Ernault Pauline, Bénifla Jean-Louis
Abstract excerpt
BACKGROUND: Coelocentesis may represent the ideal technique for very early prenatal diagnosis. Although cell density in coelomic fluid (CF) is very low, the results of analyses on the cellular compartment have been proposed for prenatal diagnosis. METHODS AND RESULTS: We aimed to evaluate the amount of total DNA (i.e. cellular and cell-free) in 14 samples (0.4-0.8 ml) of CF, taken from women at 8- to 9-week...
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