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Isolation and whole genome sequencing of fetal cells from maternal blood towards the ultimate non‐invasive prenatal testing

16 Nov 2017

Abstract excerpt

OBJECTIVE: The purpose of this study were to develop a methodology of isolating fetal cells from maternal blood and use deep sequence demonstrating the promise for complete and accurate genetic screening compared to other non-invasive prenatal testing. METHODS: Here in this study, we developed a double negative selection (DNS) procedure to unbiasedly enrich fetal cells. After validated by short tandem repeat...

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PMID: 29144536
DOI: 10.1002/pd.5186

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