Article
The association between multidrug resistance-1 gene polymorphisms and outcomes of allogeneic HLA-identical stem cell transplantation.
Haematologica - 1 Jun 2006
Kim Dong Hwan, Park Jae Yong, Sohn Sang Kyun, Lee Nan Young, Suh Jang Soo, Lee Kyu Bo
Abstract excerpt
The impact of single nucleotide polymorphisms of two loci (C3435T and G2677T/A) of the multidrug resistance-1 gene (MDR1) was investigated in 82 patients undergoing allogeneic stem cell transplantation (SCT). The GG genotype on G2677T/A loci was associated with higher non-relapse mortality than w...
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