Article
Roles for APIS and the 20S proteasome in adenovirus E1A-dependent transcription.
The EMBO journal - 21 Jun 2006
Rasti Mozhgan, Grand Roger J A, Yousef Ahmed F, Shuen Michael, Mymryk Joe S, Gallimore Phillip H, Turnell Andrew S
Abstract excerpt
We have determined distinct roles for different proteasome complexes in adenovirus (Ad) E1A-dependent transcription. We show that the 19S ATPase, S8, as a component of 19S ATPase proteins independent of 20S (APIS), binds specifically to the E1A transactivation domain, conserved region 3 (CR3). Re...
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