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Article

Social interactions among epithelial cells during tracheal branching morphogenesis.

Nature - 8 Jun 2006

Ghabrial Amin S, Krasnow Mark A

Abstract excerpt

Many organs are composed of tubular networks that arise by branching morphogenesis in which cells bud from an epithelium and organize into a tube. Fibroblast growth factors (FGFs) and other signalling molecules have been shown to guide branch budding and outgrowth, but it is not known how epithelial cells coordinate their movements and morphogenesis. Here we use genetic mosaic analysis in Drosophila melanogaster...

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PMID: 16760977
DOI: 10.1038/nature04829

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