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Article

Drosophila syndecan regulates tracheal cell migration by stabilizing Robo levels.

EMBO reports - 30 Sept 2011

Schulz Joachim G, Ceulemans Helga, Caussinus Emmanuel, Baietti Maria F, Affolter Markus, Hassan Bassem A, David Guido

Abstract excerpt

Here we identify a new role for Syndecan (Sdc), the only transmembrane heparan sulphate proteoglycan in Drosophila, in tracheal development. Sdc is required cell autonomously for efficient directed migration and fusion of dorsal branch cells, but not for dorsal branch formation per se. The cytoplasmic domain of Sdc is dispensable, indicating that Sdc does not transduce a signal by itself. Although the...

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Identifiers

PMID: 21836636
DOI: 10.1038/embor.2011.153
PMCID: PMC3185339

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Source receipt: pubmed, retrieved 7 Sept 2026.

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