Article
Comparison of PCR-RFLP and Genescan-based genotyping for analyzing infection dynamics of Plasmodium falciparum.
The American journal of tropical medicine and hygiene - 1 Jun 2006
Falk Nicole, Maire Nicolas, Sama Wilson, Owusu-Agyei Seth, Smith Tom, Beck Hans-Peter, Felger Ingrid
Abstract excerpt
Parameters describing the infection dynamics of Plasmodium falciparum are important determinants of the potential impact of interventions and are potential outcome measurements for malaria intervention trials. Low parasite densities, periodic sequestration of parasites, and the presence of multiple concurrent infections make it essential to use molecular techniques to estimate the force of infection and duration...
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