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Article

Structural basis of substrate specificity in human glyoxylate reductase/hydroxypyruvate reductase.

Journal of molecular biology - 30 Jun 2006

Booth Michael P S, Conners R, Rumsby Gill, Brady R Leo

Abstract excerpt

Human glyoxylate reductase/hydroxypyruvate reductase (GRHPR) is a D-2-hydroxy-acid dehydrogenase that plays a critical role in the removal of the metabolic by-product glyoxylate from within the liver. Deficiency of this enzyme is the underlying cause of primary hyperoxaluria type 2 (PH2) and lead...

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Source

Identifiers

PMID: 16756993
DOI: 10.1016/j.jmb.2006.05.018

Genes

GRHPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16756993-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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