Article
Polymerase chain reaction and allele-specific oligonucleotides in paternity testing of the deceased.
Transfusion - 1 Jun 1991
Howard P L, Collins C C, Heintz N H
Abstract excerpt
The assignment of paternity when the alleged father has died is now possible by use of a variety of allele-specific oligonucleotides after amplification of genomic DNA by the polymerase chain reaction (PCR). Issues relating to the inheritance of estates may be decided on fact rather than allegation. PCR-based genotyping of DQ alpha haplotypes from paraffin-embedded tissue of the deceased was used to prove...
Topics
- Alleles
- Deoxyribonucleases, Type II Site-Specific
- Factor VIII
- Female
- Genotype
- HLA-DQ Antigens
- Humans
- Infant, Newborn
- Male
- Oligonucleotide Probes
- Paternity
- Polymerase Chain Reaction