Article
Polymerase chain reaction (PCR) amplification and human leukocyte antigen (HLA)-DQ alpha oligonucleotide typing on biological evidence samples: casework experience.
Journal of forensic sciences - 1 May 1992
Blake E, Mihalovich J, Higuchi R, Walsh P S, Erlich H
Abstract excerpt
The polymerase chain reaction (PCR) method of specific gene amplification was used in casework to synthesize millions of copies of the polymorphic second exon of the human leukocyte antigen (HLA)-DQ alpha (or DQA1) locus from a variety of evidence samples. The HLA-DQ alpha allelic variants in the...
Topics
- Adolescent
- Alleles
- Child
- Child, Preschool
- DNA
- Exons
- Female
- Forensic Medicine
- Gene Amplification
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- Humans
- Male
- Nucleic Acid Hybridization
- Oligonucleotide Probes
- Polymerase Chain Reaction
- Reproducibility of Results