Article
Amplification of three hypervariable DNA regions by polymerase chain reaction for paternity determinations: comparison with conventional methods and DNA fingerprinting.
Molecular and cellular probes - 1 Feb 1992
Helminen P, Sajantila A, Johnsson V, Lukka M, Ehnholm C, Peltonen L
Abstract excerpt
The present study evaluates the usefulness of a PCR-based method for routine paternity testing in 35 paternity cases. This identification method which is based on amplification of three hypervariable genetic loci, apoB, D1S80 and HLA-DQ alpha, is compared, with regard to reliability and technical...
Topics
- Blood Grouping and Crossmatching
- Blotting, Southern
- DNA
- DNA Fingerprinting
- Genetic Variation
- Humans
- Male
- Paternity
- Polymerase Chain Reaction
- Repetitive Sequences, Nucleic Acid