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Article

The role of proline residues in the dynamics of transmembrane helices: the case of bacteriorhodopsin.

Molecular membrane biology - 1 Jan 2000

Perálvarez-Marín Alex, Bourdelande José-Luis, Querol Enric, Padrós Esteve

Abstract excerpt

Proline residues in transmembrane helices have been found to have important roles in the functioning of membrane proteins. Moreover, Pro residues occur with high frequency in transmembrane alpha-helices, as compared to alpha-helices for soluble proteins. Here, we report several properties of the bacteriorhodopsin mutants P50A (helix B), P91A (helix C) and P186A (helix F). Compared to wild type, strongly perturbed...

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Identifiers

PMID: 16754356
DOI: 10.1080/09687860500435019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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