Mutators and long-term molecular evolution of pathogenic Escherichia coli O157:H7.

doi:10.3201/eid0404.980411

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Article

Mutators and long-term molecular evolution of pathogenic Escherichia coli O157:H7.

Emerging infectious diseases - 1 Jan 2000

Whittam T S, Reid S D, Selander R K

Abstract excerpt

It has been proposed that an increased mutation rate (indicated by the frequency of hypermutable isolates) has facilitated the emergence of Escherichia coli O157:H7. Analysis of the divergence of 12 genes shows no evidence that the pathogen has undergone an unusually high rate of mutation and mol...

Topics

Escherichia coli O157
Evolution, Molecular
Genes, Bacterial
Humans
Mutation

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