Article
High KIR diversity in Amerindians is maintained using few gene-content haplotypes.
Immunogenetics - 1 Jun 2006
Gendzekhadze Ketevan, Norman Paul J, Abi-Rached Laurent, Layrisse Zulay, Parham Peter
Abstract excerpt
Interaction between killer cell immunoglobulin-like receptors (KIR) and cognate HLA class I ligands influences the innate and adaptive immune response to infection. The KIR family varies in gene content and allelic polymorphism, thereby, distinguishing individuals and populations. KIR gene content was determined for 230 individuals from three Amerindian tribes from Venezuela: the Yucpa, Bari and Warao....
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