Article
Human cytomegalovirus (HCMV) UL82 gene product (pp71) relieves hDaxx-mediated repression of HCMV replication.
Journal of virology - 1 Jun 2006
Cantrell Stacy R, Bresnahan Wade A
Abstract excerpt
This study examines the role of the cellular protein hDaxx in controlling human cytomegalovirus (HCMV) immediate-early (IE) gene expression and viral replication. Using permissive cell lines that either overexpress hDaxx or are depleted of hDaxx expression by the use of short hairpin RNA, we demonstrate that hDaxx functions as a repressor of HCMV IE gene expression and replication. In addition, we demonstrate...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
