Article
Bases of biocontrol: sequence predicts synthesis and mode of action of agrocin 84, the Trojan horse antibiotic that controls crown gall.
Proceedings of the National Academy of Sciences of the United States of America - 6 Jun 2006
Kim Jung-Gun, Park Byoung Keun, Kim Sung-Uk, Choi Doil, Nahm Baek Hie, Moon Jae Sun, Reader John S, Farrand Stephen K, Hwang Ingyu
Abstract excerpt
Agrobacterium radiobacter K84, used worldwide to biocontrol crown gall disease caused by Agrobacterium tumefaciens, produces an antiagrobacterial compound called agrocin 84. We report the nucleotide sequence of pAgK84, a 44.42-kb plasmid coding for production of this disubstituted adenine nucleotide antibiotic. pAgK84 encodes 36 ORFs, 17 of which (agn) code for synthesis of or immunity to agrocin 84. Two genes,...
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